NIH/NHLBI SBIR/STTR – Maternal Health Technologies (Parent SBIR PA-27-100)

Amount

Up to $2.5M

Phase I ~$275K; non-dilutive

Deadline

Rolling

Odds

~15–20% Phase I

Effort

1–2 days

Can you get this?

✓For small business entrepreneurs only

✓Research must address heart, lung, blood, or sleep disorders

✓Funding is non-dilutive; no equity required

✓STTR track requires a research institution partner

✓Early-stage research and development focus

Your real odds

Phase I award rates run 15–20% across NIH SBIR/STTR programs, so expect real competition.

The maternal health NOSI is a special interest notice layered on top of parent SBIR solicitations, so you compete in the broader applicant pool while signaling relevance to a priority area. Strong preliminary data and a clear commercialization path meaningfully improve scores.

What it takes

Confirm eligibility and identify the right solicitation (SBIR vs. STTR, clinical trial allowed or not)1–2 days

Develop specific aims and consult NHLBI program officers (nhlbi_sbir@mail.nih.gov) before submitting2–4 weeks

Prepare and submit full application via grants.gov, including research plan, commercialization plan, and budget2–4 months

Worth knowing

NHLBI's Innovation and Commercialization Office offers direct services to applicants before and after award, and contacting them early can sharpen your application and surface fit issues before you spend months writing.

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