NIH Phase IIB Strategic Breakthrough Award (PA-27-101)

Amount

Up to $30M

Institute ceilings; 100%

Deadline

Date not announced

Can you get this?

✓For small businesses developing health-related technologies

✓STTR requires nonprofit research institution partnership

✓Phase IIB requires prior NIH SBIR/STTR funding

✓Phase IIB requires 100% matching funds

✓HHS limits submissions to 9 per small business per fiscal year

What it takes

Complete all required registrations: System for Award Management (SAM), Unique Entity Identifier (UEI), SBA Company Registry, eRA Commons, and Grants.gov.Six weeks or longer

Ensure all Senior/Key Personnel have an ORCID iD linked to their eRA Commons profile before submission.

Identify the appropriate NIH Institute or Center using the Small Business Funding Considerations and Contacts resource and contact Program Officials before preparing an application.

Submit the application by a standard due date; small business applications will not be accepted late under NIH's updated policy.

Worth knowing

HHS now limits SBIR/STTR submissions to 9 per small business per fiscal year across all HHS affiliates and activity codes. Foreign disclosure requirements have also expanded to include cybersecurity practices, patent analysis, foreign ownership, and certain business relationships with foreign countries of concern.

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